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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2503 | PAC-1 | Procaspase activating compound 1 | Apoptosis , Caspase , Autophagy |
PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others. | |||
T18603 | PROTAC BRD4 degrader for PAC-1 | Others | |
PROTAC BRD4 degrader for PAC-1 (compound 5) is a chimeric BET degrader GNE-987 conjugated with a disulfide-containing linker[1]. This PROTAC-linker conjugate specifically targets and degrades BRD4, enabling selective pro... | |||
T50096 | 1,3,3,5,5-pentamethylcyclohexan-1-amine hydrochloride | Others | |
1,3,3,5,5-pentamethylcyclohexan-1-amine hydrochloride, also known as PAC, is a cyclic amine commonly used as a chiral auxiliary in asymmetric syntheses including the Diels-Alder reaction, hydroxyaldol reaction, and Micha... | |||
T2238 | Cariporide | HOE-642 | Sodium Channel |
Cariporide (HOE-642) (HOE-642), an effective NHE1 inhibitor, has inhibitory effects on the degranulation of human platelets, the formation of platelet-leukocyte-aggregates, and the activation of the GPIIb/IIIa receptor (... | |||
T18607 | PROTAC ER Degrader-3 | Others | |
PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to an antibody. Notably, when PAC is conjugated to an antibody,... | |||
T18606 | PROTAC ER Degrader-2 | Others | |
PROTAC ER Degrader-2 serves as a synthesis intermediate for the production of PAC, a compound that incorporates the ADCs linker and PROTACs, which are subsequently conjugated to an antibody. PAC, exhibits a greater capab... | |||
T37139 | 5'-O-DMT-PAC-dA | ||
5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1]. [1]. Schulhof JC, et, al. The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile... |